Alina BEŞLIU, Nadejda EFREMOVA, Agafia USATÎI, Ludmila BATÎR


În lucrare sunt prezentate informații noi despre influența nanoparticulelor de ZnO cu dimensiuni de <50 nm și <100 nm asupra levurii pigmentate Rhodotorula gracilis CNMN-Y-03. S-a constatat că viabilitatea, conținutul de pigmenți caro­te­­noidici și carbohidrați la tulpina în studiu se modifică în funcție de dimensiunile și concentrațiile utilizate. S-a demonstrat că viabilitatea celulelor levuriene depinde de timpul de contact pentru ambele tipuri de nanoparticule utilizate. Rezul­tatele au pus în evidență că concentrațiile de 1-20 mg/l sporesc cantitatea de carbohidrați și mențin la nivelul probei de control conținutul pigmenților carotenoidici, pe când concentrațiile de 30-70 mg/l devin toxice pentru tulpina studiată.




The paper provides new information on the influence of ZnO nanoparticles of <50 nm and <100 nm on pigmented yeast Rhodotorula gracilis CNMN-Y-03. It has been established that the viability, carotenoid and carbohydrate content of the strain has changed according to the size and used concentration. It has been demonstrated that the viability of yeast cells depends on the contact time for both types of nanoparticles. The results have highlighted that concentrations of 1-20 mg/l increased the amount of carbohydrates and maintained the content of carotenoid pigments at the level of the control sample, whereas the concentrations of 30-70 mg/l become toxic for the studied strain.


Rhodotorula gracilis, ZnO nanoparticles, cytotoxicity, cell viability, carotenoid pigments, carbohydrates.

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