Olga Burduniuc


În prezenta lucrare sunt analizate cele mai relevante publicații din literatura medicală selectate printr-o cercetare utili­zând bazele de date PubMed, EMBASE, HINARI și site-urile web ale OMS, CDC privind unul dintre factorii de viru­lenţă a fungilor precum formarea biofilmelor. Scopul acestui review este de a furniza informație științifică actuală re­fe­ritore la acest subiect. Au fost revizuite un șir de studii și s-a constatat că ambele tipuri de fungi – atât levuriformi, cât și filamentoși – pot adera la suprafețe biotice și abiotice, dezvoltându-se în comunități extrem de organizate, rezistente la preparatele antimicotice și la factorii de mediu. 



This paper is a literature review that analyzes the most relevant publications in the medical literature, selected through a search in databases such as PubMed EMBASE, HINARI, WHO and CDC websites regarding one of the fungal virulence factors - biofilm formation. The purpose of this review is to provide up-to-date scientific information on this topic. In carrying out these objectives, a series of studies were reviewed and it was found that both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing in highly organized communities, resistant to antifungal drugs and environmental factors.


fungi, biofilms, persistence, resistance to antifungals.

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