În articol este efectuată analiza literaturii de specialitate privind sinteza, caracterizarea structurală și proprietățile bio­lo­gice ale compușilor coordinativi ai cuprului(II) în baza tiosemicarbazonelor 2-formilpiridinei și a derivaților ei. A fost stabilit că activitatea biologică a compușilor coordinativi depinde de compoziția și structura complecșilor, în special de natura substituenților din fragmentul piridinic și a substituenților la atomul de azot N(4) ai tiosemicarbazonelor.



The paper focuses on the analysis of the literature on the synthesis, structural characterisation and biological properties of coordination compounds of copper (II) with 2-formylpyridine thiosemicarbazones and its derivatives. It has been established that biological activity of the coordination compounds dependents on the composition and structure of the complexes, especially on the substituents in the pyridine fragment and on the N(4) nitrogen atom of the thiosemicarbazones.


coordination compounds, copper (II), thiosemicarbazones, 2-formylpyridine, crystal structure, biological activity.

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